Enterovirus D68 and acute flaccid myelitis—evaluating the evidence for causality
نویسندگان
چکیده
منابع مشابه
The association between acute flaccid myelitis (AFM) and Enterovirus D68 (EV-D68) – what is the evidence for causation?
BackgroundEnterovirus D68 (EV-D68) has historically been a sporadic disease, causing occasional small outbreaks of generally mild infection. In recent years, there has been evidence of an increase in EV-D68 infections globally. Large outbreaks of EV-D68, with thousands of cases, occurred in the United States, Canada and Europe in 2014. The outbreaks were associated temporally and geographically...
متن کاملEnterovirus D68–Associated Acute Flaccid Myelitis in Immunocompromised Woman, Italy
In Italy in 2016, acute flaccid myelitis developed in a woman who had received a hematopoietic stem cell transplant. Enterovirus D68 viral genome was detected in respiratory and cerebrospinal fluid samples, and the viral protein 1 sequence clustered with lineage B3. Immunocompromised adults may be at risk for enterovirus D68-associated neurologic complications.
متن کاملAcute flaccid paralysis following enterovirus D68 associated pneumonia, France, 2014.
Human enterovirus D68 (EV-D68) is known to be associated with mild to severe respiratory infections. Recent reports in the United States and Canada of acute flaccid paralysis (AFP) in children with detection of EV-D68 in respiratory samples have raised concerns about the aetiological role of this EV type in severe neurological disease. This case study is the first report of AFP following EV-D68...
متن کاملAcute flaccid paralysis in a child infected with enterovirus D68: A case report
bc medical journal vol. 56 no. 10, december 2014 bcmj.org ABSTRACT: Enterovirus D68 is increasingly being reported as a cause of severe respiratory illness across North America, with several children in Canada testing positive for this virus and experiencing concurrent polio-like symptoms. In one recent case in British Columbia, a 9-yearold patient presented with acute flaccid paralysis of his ...
متن کاملRe-analysis of metagenomic sequences from acute flaccid myelitis patients reveals alternatives to enterovirus D68 infection
Metagenomic sequence data can be used to detect the presence of infectious viruses and bacteria, but normal microbial flora make this process challenging. We re-analyzed metagenomic RNA sequence data collected during a recent outbreak of acute flaccid myelitis (AFM), caused in some cases by infection with enterovirus D68. We found that among the patients whose symptoms were previously attribute...
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ژورنال
عنوان ژورنال: The Lancet Infectious Diseases
سال: 2018
ISSN: 1473-3099
DOI: 10.1016/s1473-3099(18)30094-x